From Phoenix, head northeast on Hwy. 87 to Payson and then continue east on Hwy. 260 through Show Low, (spend the night in Snowflake Rt 77).Go back to 260 through Lakeside, Pinetop, and Greer to Springerville and Eagar From here, head south on Hwy. 191, through Clifton and Morenci, to Hwy 70 west. Follow Hwy. 70 west through Safford to Globe, where Hwy. 60 continues back to Phoenix.
From Tucson, take the Mt. Lemmon Highway from the northeast edge of the city. To reach Madera Canyon, drive south on I-19 to exit 63 and go east for 11 miles. To reach Mt. Graham, drive east on I-10 to just beyond Willcox and then go north on Hwy. 191 to Hwy. 366.
To reach the Grand Canyon from Phoenix, head north on I-17 to Flagstaff and then take Hwy. 180 north to the South Rim. To reach the North Rim from Flagstaff, go north on Hwy. 89, take Hwy. 89A west to Jacob Lake, and then go south on Hwy. 67. 10 to Willcox. From Willcox, continue west on I-10 to return to Tucson.